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MICS™ Minimally Invasive Cochlear System
MICS places our local formulations at the round window membrane, the entry point to the inner ear, under direct visualization. Each formulation is matched to its drug substance.Intratympanic administration is performed in the clinic under local anesthesia.
Direct visualization at the round window membrane
Until now, physicians had to choose between placing a drug blind in the clinic or precisely in the operating room. MICS brings precise placement into the clinic.
Intratympanic injection
Performed blind. The physician cannot see whether the drug reaches the round window membrane.
- Round window visualized No
- Performed in the clinic Yes
Surgical approach
Precise placement, but it requires an operating room.
- Round window visualized Yes
- Performed in the clinic No
MICS™
The single-use MICS Applicator combines a camera, illumination and an injection cannula, so the physician sees the round window membrane while placing the formulation on it, under local anesthesia.
- Round window visualized Yes
- Performed in the clinic Yes
One system across drug classes
MICS places the right drug at the right target. Each drug substance is paired with a formulation suited to it, so the same system works with small molecules, proteins and advanced therapies.
MICS™ + formulations tailored to each drug
Small molecules
Formulations of approved and novel agents, including our most advanced program.
SPT-2101 · SPT-5108Proteins
Neurotrophins and other biologics, where formulation and local exposure are the bottleneck.
SPT-4106Advanced therapies
Gene and cell therapies, where precise delivery matters most.
In evaluationAccess is what has held the field back
The biology of inner ear disease is better understood than ever, and promising molecules exist. What has been missing is a reliable way to place enough drug at the inner ear. MICS and our local formulations are designed to address that, so more inner ear therapies can reach patients.
See our pipeline