SOUTH SAN FRANCISCO, Calif., Feb. 06, 2023 — Spiral Therapeutics, Inc. (“Spiral”), a clinical-stage company delivering therapies for inner ear disorders, today announced a presentation at the upcoming Association for Research in Otolaryngology (ARO) 46th Annual MidWinter Meeting, to be held February 11-15, 2023 in Orlando, FL.

Dr. Isabel Varela-Nieto will present a poster related to Spiral’s SPT-2101 program for Meniere’s disease with title “Intratympanic Single Dosage of Dexamethasone Formulated as SPT-2101 Protects Against LPS-Induced Alteration of the Blood-Labyrinth Barrier”

Date: Saturday, February 11, 2023

Time: All Day

Location: SA157

Dr. Isabel Varela-Nieto is a Professor of Research at the CSIC and group leader at the CIBER of rare diseases (CIBERER, ISCIII) in Madrid. From the early 1990s she has been studying hearing neurobiology and IGF-1 actions. She was the first Chair of the SEBBM Science for Society working group with which she actively collaborates, and member of the FEBS Network working group. She is currently the president of the SEBBM, a member of the FEBS Science and Society Committee and of the ISC Finances Committee.

About Spiral Therapeutics

Spiral Therapeutics is a clinical-stage company delivering therapies for inner ear disorders. Spiral’s novel drug delivery platform allows for minimally invasive, precise and durable exposure of drugs to the cochlea. Spiral is advancing a therapeutic pipeline with focus on balance disorders and hearing loss. Spiral’s lead program, SPT-2101, is a sustained-release steroid formulation for the treatment of Meniere’s disease. For more information, visit: www.spiraltx.com